Photoshop for raster effects. Emptying out eyeballs and such.
Illustrator for text and layout. <<
hypnohub.net/post/show/45...e-breasts-brown_hair-coll| It turns out that simple things aren't trivial, and you need the right tool for the job.>>
I've heard a lot of people have had success with Gimp in place of Photoshop. I just happen to own a license of CS5 and like the UI a bit better.
I do not yet know of something I would endorse in place of illustrator for vector illustration and typesetting. Inkscape fails in this regard and has for nearly a decade - its UI isn't necessarily bad but the thing fails constantly on a windows system, even at .9x. Haven't tested it on linux, might have better luck there, but that's contingent on your willingness to experiment. Xara used to offer a free linux package of their program that might be worth checking out. If someone else knows, I'd be interested to hear about it.